Scott Barbee photo

Scott Barbee

Associate Professor

  • Faculty

What I do

The Barbee lab focuses on understanding roles for RNA/protein interactions in Drosophila models for neurodevelopment and neurodegeneration.


Neurodevelopment, neurodegeneration, RNA biology


  • Ph.D., Cell and Developmental Biology, University of Colorado Health Sciences Center, 2004
  • MS, Zoology and Physiology, University of Wyoming, 1998

Professional Affiliations

  • Front Range Neuroscience Group
  • RNA Society


The Barbee lab uses Drosophila melanogaster and a model to understand the role of RNA/protein granules in neurons.

Key Projects

  • Exploring roles for FMR/P-bodies in presynaptic development

Featured Publications

Nesler, K. R., Starke, E. L., Boin, N. G., Ritz, M., & Barbee, S. A. (2016). Presynaptic CamKII regulates activity-dependent axon terminal growth. Molecular and cellular neurosciences, 76, 33-41.
Nesler, K. R., Sand, R. I., Symmes, B., Boin, N., Laun, A. E., & Barbee, S. A. (2013). The miRNA Pathway Controls Rapid Changes in Activity-Dependent Synaptic Structure at the Drosophila melanogaster Neuromuscular Junction. PLoS ONE, 8(7), e68385.
Pradhan, S. J., Nesler, K. R., Rosen, S. F., Kato, Y., Nakamura, A., Ramaswami, M., & Barbee, S. A. (2012). The conserved P body component HPat/Pat1 negatively regulates synaptic terminal growth at the larval Drosophila neuromuscular junction. Journal of Cell Science, 125(24), 6105-6116.
Barbee, S. A., Extes, P. S., Cziko, A. -M., Hillebrand, J., Luedeman, R. A., Coller, J. M., et al. (2006). Staufen- and FMRP-containing neuronal RNPs are structurally and functionally related to somatic P-bodies. Neuron, 52(6), 997-1009.