Dinah Loerke

Associate Professor

Faculty

Physics Building, 2112 E. Wesley Ave. Denver, CO 80208

What I do

Associate Professor with a research and teaching focus on biophysics, biomechanics, imaging, and quantitative computational analysis and modeling

Specialization(s)

biophysics, imaging

Degree(s)

Ph.D., Biophysics, University of Goettingen, 2004
MS, Physics, University of Goettingen, 1998

Licensure / Accreditations

IRBNet Board SL-1 Lab Certification
Adult CPR/AED

Research

molecular and mechanical regulation of morphogenesis, regulation of clathrin-coated pit maturation

Key Projects

The Biomechanics of Intercalation in Germ-Bank Elongation
Deconstructing The Cell's Mechanical Circuits
Cottrell Scholar Award

Featured Publications

Jewett, C. E., Vanderleest, T. E., Miao, H., Xie, Y., Madhu, R., Loerke, D., & Blankenship, J. T. (2017). Planar polarized Rab35 functions as an oscillatory ratchet during cell intercalation in the Drosophila epithelium. Nature Communications, 8.

Kadlecova , Z., Spielman, S. J., Loerke, D., Mohanakrishnan, A., Reed, D. K., & Schmid, S. L. (2017). Regulation of clathrin-mediated endocytosis by hierarchical allosteric activation of AP2. Journal of Cell Biology.

Loerke, D., Mettlen, M., Yarar, D., Jaqaman, K., Jaqaman, H., Danuser, G., & Schmid, S. L. (2009). Cargo and dynamin regulate clathrin-coated pit maturation. PLoS biology, 7(3), e57.

Loerke, D., Mettlen, M., Schmid, S., & Danuser, G. (2011). Measuring the hierarchy of molecular events during clathrin-mediated endocytosis. Traffic, 12(7), 815-825.

Loerke, D., le Duc, Q., Blonk, I., Kerstens, A., Spanjaard, E., Machacek, M., et al. (2012). Quantitative Imaging of Epithelial Cell Scattering Identifies Specific Inhibitors of Cell Motility and Cell-Cell Dissociation. Science Signaling , 5(231).

Awards

2017 Scialog Fellow, Research Corporation for Science Advancement